Unisom SleepMelts Nighttime Sleep-Aid
Diphenhydramine Hydrochloride · Tablet, Chewable · Oral
Active ingredient
Active ingredient (in each caplet) Diphenhydramine HCI 25 mg
Purpose
Purpose Nighttime sleep-aid
Uses
Uses for relief of occasional sleeplessness
Warnings
Warnings Do not use for children under 12 years of age with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product avoid alcoholic drinks Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Do not use
Do not use for children under 12 years of age with any other product containing diphenhydramine, even one used on skin
Ask a doctor before use
Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
When using this product
When using this product avoid alcoholic drinks
Stop use and ask a doctor
Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions adults and children 12 years of age and over: 2 tablets (25 mg each) at bedtime if needed, or as directed by a doctor place 2 tablets on tongue; tablets dissolve with or without water allow tablets to dissolve in mouth or chew before swallowing
Inactive ingredients
Inactive ingredients citric acid, ethylcellulose, flavor, hydroxypropyl cellulose, mannitol, microcrystalline cellulose, PVP, red 7, starch, sucralose, sucrose (309-154) Dist. by: CHATTEM, Inc. P.O. Box 2219, Chattanooga, TN 37409 USA © 2011 Chattem Inc. www.chattem.com
Label text from the FDA structured product label by Chattem, Inc. (revised Jan 14, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 2 products
Unisom SleepMelts Nighttime Sleep-Aid NDC products (2)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 41167-0014 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Chewable | Chattem, Inc. | OTC MONOGRAPH DRUG |
| 63868-393 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Chewable | QUALITY CHOICE (CHAIN DRUG MARKETING ASSOCIATION) | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Unisom SleepMelts Nighttime Sleep-Aid used for?
Uses for relief of occasional sleeplessness
Who makes Unisom SleepMelts Nighttime Sleep-Aid?
Unisom SleepMelts Nighttime Sleep-Aid is listed by 2 labelers in the FDA NDC directory, including Chattem, Inc., QUALITY CHOICE (CHAIN DRUG MARKETING ASSOCIATION).