Vicks ZzzQuil

Diphenhydramine HCl · Liquid · Oral

Over the counter Histamine-1 Receptor Antagonist Antihistamine

Active ingredient

Active ingredients (in each tablet) Doxylamine succinate 25 mg

Purpose

Purpose Nighttime sleep-aid

Uses

Use helps to reduce difficulty in falling asleep

Warnings

Warnings Do not use in children under 12 years of age Ask a doctor before use if you have a breathing problem such as asthma, emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking any other drugs When using this product avoid alcoholic beverages take only at bedtime Stop use and ask a doctor if sleeplessness persists continuously for more than two weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding , ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Do not use

Do not use in children under 12 years of age

Ask a doctor before use

Ask a doctor before use if you have a breathing problem such as asthma, emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking any other drugs

When using this product

When using this product avoid alcoholic beverages take only at bedtime

Stop use and ask a doctor

Stop use and ask a doctor if sleeplessness persists continuously for more than two weeks. Insomnia may be a symptom of serious underlying medical illness.

Pregnancy or breast-feeding

If pregnant or breast-feeding , ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Directions

Directions adults & children 12 years of age and over: take one tablet 30 minutes before going to bed; take once daily or as directed by a doctor children under 12 years of age: do not use

Other information

Other information store at 68-77° F (20°-25° C) retain carton until time of use see carton end panel for lot number and expiration date

Inactive ingredients

Inactive ingredients anhydrous dibasic calcium phosphate, dibasic calcium phosphate dihydrate, FD&C blue no. 1 aluminum lake, magnesium stearate, microcrystalline cellulose, sodium starch glycolate

Questions?

Questions? 1-877-881-5813

Label text from the FDA structured product label by The Procter & Gamble Manufacturing Company (revised Oct 2, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Vicks ZzzQuil NDC products (9)

NDCStrength & formLabelerType
69423-902Doxylamine Succinate 25 mg/1
Tablet
The Procter & Gamble Manufacturing CompanyANDA
37000-598Diphenhydramine Hydrochloride 50 mg/30mL; Acetaminophen 1000 mg/30mL
Liquid
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
37000-974Diphenhydramine Hydrochloride 25 mg/1; Acetaminophen 500 mg/1
Tablet, Coated
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-795Diphenhydramine Hydrochloride 50 mg/30mL
Liquid
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-812Diphenhydramine Hydrochloride 50 mg/30mL
Liquid
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-830Diphenhydramine Hydrochloride 50 mg/30mL
Liquid
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-985Diphenhydramine Hydrochloride 50 mg/30mL; Acetaminophen 1000 mg/30mL
Liquid
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-306
Kit
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-372Diphenhydramine Hydrochloride 50 mg/30mL; Acetaminophen 1000 mg/30mL
Liquid
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG

Frequently asked questions

What is Vicks ZzzQuil used for?

Use helps to reduce difficulty in falling asleep

Who makes Vicks ZzzQuil?

Vicks ZzzQuil is listed by 1 labeler in the FDA NDC directory, including The Procter & Gamble Manufacturing Company.