ZyloRelief

Lidocaine Hydrochloride · Cream · Topical

Over the counter Amide Local Anesthetic Antiarrhythmic

Active ingredient

Active Ingredients Lidocaine HCL 4.0% Purpose External analgesic

Purpose

ZyloRelief Rapid-onset topical analgesic ZyloRelief should be administered under the supervision of a licensed medical practitioner.

Uses

Uses For temporary relief of pain and itching due to minor skin irritations.

Warnings

Warnings - For external use only. - Avoid contact with eyes.

Do not use

- Do not use in large quantities, particularly over raw surfaces or blistered areas.

Stop use and ask a doctor

- Stop use and ask a doctor if condition worsens, or if symptoms persist for more than week or clear up and occur again within a few days. Discontinue use.

Keep out of reach of children

- Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

Directions

Directions For adults and children two-years or older: Apply 1 packet (2 grams) topically to the affected area(s) up to 4 times daily as needed for pain. Do not use more than 4 packets (8 grams) per day.

Inactive ingredients

Inactive Ingredients Arnica Montana Extract, C13-14 Isoalkane, Dimethyl Sulfone, Emu Oil (Dromiceius), Ethoxydiglycol, Ethylhexylglycerin, Glycerin, Isopropyl Palmitate, Laureth-7, Phenoxyethanol, Polyacrylamide, Propylene Glycol, Stearic Acid, Triethanolamine, Water (Aqua)

Label text from the FDA structured product label by Highmark Pharma LLC (revised Jul 14, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

ZyloRelief NDC products (1)

NDCStrength & formLabelerType
87450-208Lidocaine Hydrochloride 4 g/100g
Cream
Highmark Pharma LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is ZyloRelief used for?

Uses For temporary relief of pain and itching due to minor skin irritations.

Who makes ZyloRelief?

ZyloRelief is listed by 1 labeler in the FDA NDC directory, including Highmark Pharma LLC.