Zyncof
Dextromethorphan HBr and Guaifenesin · Syrup · Oral
Active ingredient
Active ingredients (in each 5 mL, 1 teaspoon) Dextromethorphan HBr, 20 mg Guaifenesin, 400 mg
Purpose
Purposes Cough suppressant Expectorant
Uses
Uses
• temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold
• helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes
Warnings
Warnings
• Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have
• cough that occurs with too much phelgm (mucus)
• cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis or emphysema. When using this product, do not use more than directed. Stop use and ask a doctor if cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions
• do not take more than 6 doses in any 24-hour period.
• mL=milliliter age dose Adults and children 12 years of age and over 1 teaspoon (5 mL) every 4 hours Children under 12 years of age do not use
Other information
Other information
• Tamper evident feature: Do not use if printed security seal is torn, broken or missing.
• Store at controlled room temperature 15-30°C (59-86°F)
• Avoid excessive heat or humidity.
Inactive ingredients
Inactive ingredients citric acid, eucalyptus oil, flavors, glycerin, menthol, methylparaben, propylene glycol, propylparaben, purified water, sodium citrate, sucralose
Questions?
Questions or comments? 1-787-767-2072 You may also report serious side effects to this phone number. Call weekdays from 8AM to 4PM AST
Label text from the FDA structured product label by Kramer Novis (revised Nov 13, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Dextromethorphan Hydrobromide in 1 product
- Guaifenesin in 1 product
Zyncof NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 52083-400 | Dextromethorphan Hydrobromide 20 mg/5mL; Guaifenesin 400 mg/5mL Syrup | Kramer Novis | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Zyncof used for?
Uses • temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold • helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes
Who makes Zyncof?
Zyncof is listed by 1 labeler in the FDA NDC directory, including Kramer Novis.