Aspirin 81
Aspirin · Tablet · Oral
Active ingredient
Active ingredient (in each tablet) Aspirin 81 mg (NSAID*) *nonsteroidal anti-inflammatory drug
Purpose
Purpose Pain reliever
Uses
Uses for the temporary relief of minor aches and pains or as recommended by your doctor
Warnings
Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: hives facial swelling shock asthma (wheezing) Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you take a blood thinning (anticoagulant) or steroid drug are age 60 or older take more or for a longer time than directed take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have had stomach ulcers or bleeding problems have 3 or more alcoholic drinks every day while using this product Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma Ask a doctor or pharmacist before use if you are taking a prescription drug for diabetes gout arthritis Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding: feel faint vomit blood have bloody or black stools have stomach pain that does not get better ringing in the ears or a loss of hearing occurs pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present any new symptoms appear If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Do not use
Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer
Ask a doctor before use
Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking a prescription drug for diabetes gout arthritis
Stop use and ask a doctor
Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding: feel faint vomit blood have bloody or black stools have stomach pain that does not get better ringing in the ears or a loss of hearing occurs pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present any new symptoms appear
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions do not take more than directed drink a full glass of water with each dose adults and children 12 years and over: take 4 to 8 tablets every 4 hours not to exceed 48 tablets in 24 hours unless directed by a doctor children under 12 years: do not use unless directed by a doctor
Other information
Other information store at 25ºC (77ºF); excursions permitted between 15º-30ºC (59º-86ºF) see end flap for expiration date and lot number
Inactive ingredients
Inactive ingredients colloidal anhydrous silica, corn starch, FD&C red #40, FD&C yellow #6, hypromellose, methacrylic acid, microcrystalline cellulose, polydextrose, polyethylene glycol, shellac wax, simethicone, sodium bicarbonate, sodium lauryl sulfate, talc, titanium dioxide, triacetin, triethyl citrate
Questions?
Questions or comments? 1-800-426-9391 8:30 AM-4:00 PM ET, Monday-Friday
Label text from the FDA structured product label by Amerisource Bergen (revised Jun 15, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Aspirin in 3 products
Aspirin 81 NDC products (3)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 46122-598 | Aspirin 81 mg/1 Tablet, Delayed Release | Amerisource Bergen | OTC MONOGRAPH DRUG |
| 57237-302 | Aspirin 81 mg/1 Tablet | Rising Pharma Holdings, Inc. | OTC MONOGRAPH DRUG |
| 0363-6452 | Aspirin 81 mg/1 Tablet | WALGREENS | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Aspirin 81 used for?
Uses for the temporary relief of minor aches and pains or as recommended by your doctor
Who makes Aspirin 81?
Aspirin 81 is listed by 3 labelers in the FDA NDC directory, including Amerisource Bergen, Rising Pharma Holdings, Inc., WALGREENS.