Daytime Cold and Flu
Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine HCl · Capsule, Liquid Filled · Oral
Active ingredient
Active ingredients (in each caplet) Acetaminophen 325 mg Dextromethorphan HBr 10 mg
Purpose
Purpose Pain reliever/fever reducer Cough suppressant
Uses
Uses
• temporarily relieves common cold/flu symptoms:
• cough due to minor throat and bronchial irritation
• sore throat
• headache
• minor aches and pains
• fever
Warnings
Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
• more than 4,000 mg of acetaminophen in 24 hours
• with other drugs containing acetaminophen
• 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
• skin reddening
• blisters
• rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use
• with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
• if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
• if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have
• liver disease
• cough that occurs with too much phlegm (mucus)
• persistent or chronic cough such as occurs with smoking, asthma, or emphysema Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin Stop use and ask a doctor if
• pain or cough gets worse or lasts more than 7 days
• fever gets worse or lasts more than 3 days
• redness or swelling is present
• new symptoms occur
• cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Do not use
Do not use
• with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
• if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
• if you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use
Ask a doctor before use if you have
• liver disease
• cough that occurs with too much phlegm (mucus)
• persistent or chronic cough such as occurs with smoking, asthma, or emphysema
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin
Stop use and ask a doctor
Stop use and ask a doctor if
• pain or cough gets worse or lasts more than 7 days
• fever gets worse or lasts more than 3 days
• redness or swelling is present
• new symptoms occur
• cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
Directions
• take only as directed - see overdose warning
• do not exceed 8 caplets per 24 hrs adults & children 12 yrs & over 2 caplets with water every 4 hrs children 4 to under 12 yrs ask a doctor children under 4 yrs do not use
Inactive ingredients
Inactive ingredients colloidal silicon dioxide, croscarmellose sodium, crospovidone, FD&C yellow #6 aluminum lake, flavor, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350, polyvinyl alcohol, povidone, pregelatinized starch, propylene glycol, stearic acid, sucralose, talc, titanium dioxide
Questions?
Questions or comments? 1-800-719-9260
Label text from the FDA structured product label by Amazon.com Services LLC (revised Aug 27, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Acetaminophen in 48 products
- Dextromethorphan Hydrobromide in 48 products
- Phenylephrine Hydrochloride in 40 products
- Guaifenesin in 2 products
Daytime Cold and Flu NDC products (48)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 69168-474 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1 Capsule, Liquid Filled | Allegiant Health | OTC MONOGRAPH DRUG |
| 69168-417 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule | Allegiant Health | OTC MONOGRAPH DRUG |
| 72288-866 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Solution | Amazon.com Services LLC | OTC MONOGRAPH DRUG |
| 72288-710 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1 Tablet, Film Coated | Amazon.com Services LLC | OTC MONOGRAPH DRUG |
| 63941-466 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | Best Choice (Valu Merchandisers Company) | OTC MONOGRAPH DRUG |
| 21130-947 | Acetaminophen 325 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL Liquid | BETTER LIVING BRANDS, LLC | OTC MONOGRAPH DRUG |
| 37835-527 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | BI-MART | OTC MONOGRAPH DRUG |
| 72476-898 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Care One (Retail Business Services, LLC.) | OTC MONOGRAPH DRUG |
| 51316-897 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1 Capsule, Liquid Filled | CVS Pharmacy | OTC MONOGRAPH DRUG |
| 69842-897 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | CVS Pharmacy | OTC MONOGRAPH DRUG |
| 69842-848 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | CVS Pharmacy | OTC MONOGRAPH DRUG |
| 51316-896 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | CVS PHARMACY, INC | OTC MONOGRAPH DRUG |
| 51316-466 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | CVS PHARMACY, INC | OTC MONOGRAPH DRUG |
| 51316-421 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL Liquid | CVS PHARMACY, INC | OTC MONOGRAPH DRUG |
| 51316-350 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Solution | CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED | OTC MONOGRAPH DRUG |
| 51316-676 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1 Tablet, Film Coated | CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED | OTC MONOGRAPH DRUG |
| 55910-982 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | OTC MONOGRAPH DRUG |
| 49035-466 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC) | OTC MONOGRAPH DRUG |
| 55319-967 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Family Dollar (FAMILY WELLNESS) | OTC MONOGRAPH DRUG |
| 55319-960 | Acetaminophen 650 mg/30mL; Dextromethorphan Hydrobromide 20 mg/30mL; Phenylephrine Hydrochloride 10 mg/30mL Liquid | Family Dollar (FAMILY WELLNESS) | OTC MONOGRAPH DRUG |
| 81522-898 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | FSA Store Inc. (Caring Mills) | OTC MONOGRAPH DRUG |
| 85828-417 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule | Grocery Outlet | OTC MONOGRAPH DRUG |
| 85828-772 | Phenylephrine Hydrochloride 5 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Acetaminophen 325 mg/15mL Liquid | Grocery Outlet, Inc. | OTC MONOGRAPH DRUG |
| 69256-466 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | Harris Teeter, LLC | OTC MONOGRAPH DRUG |
| 53345-025 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. | OTC MONOGRAPH DRUG |
| 53345-004 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. | OTC MONOGRAPH DRUG |
| 53345-056 | Dextromethorphan Hydrobromide 10 mg/1; Acetaminophen 325 mg/1 Capsule, Liquid Filled | Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd | OTC MONOGRAPH DRUG |
| 41226-772 | Phenylephrine Hydrochloride 5 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Acetaminophen 325 mg/15mL Liquid | Kroger | OTC MONOGRAPH DRUG |
| 41226-693 | Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1; Acetaminophen 325 mg/1 Capsule, Liquid Filled | Kroger Company | OTC MONOGRAPH DRUG |
| 66715-6931 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | Lil' Drug Store Products, Inc | OTC MONOGRAPH DRUG |
| 66715-6715 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 15 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Lil' Drug Store Products, Inc. | OTC MONOGRAPH DRUG |
| 66715-6815 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Lil' Drug Store Products, Inc. | OTC MONOGRAPH DRUG |
| 41250-656 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Solution | Meijer Distribution Inc | OTC MONOGRAPH DRUG |
| 41250-603 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Guaifenesin 200 mg/15mL; Phenylephrine… Solution | Meijer Distribution Inc | OTC MONOGRAPH DRUG |
| 79481-5303 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL Solution | Meijer, Inc. | OTC MONOGRAPH DRUG |
| 49580-0466 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | P & L Development, LLC | OTC MONOGRAPH DRUG |
| 59726-850 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | P & L Development, LLC | OTC MONOGRAPH DRUG |
| 51013-666 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1 Capsule, Liquid Filled | PuraCap Pharmaceutical LLC | OTC MONOGRAPH DRUG |
| 63868-020 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | QUALITY CHOICE (Chain Drug Marketing Association) | OTC MONOGRAPH DRUG |
| 83324-145 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | QUALITY CHOICE (Chain Drug Marketing Association) | OTC MONOGRAPH DRUG |
| 83324-167 | Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL; Phenylephrine Hydrochloride 5 mg/15mL Liquid | QUALITY CHOICE (Chain Drug Marketing Association) | OTC MONOGRAPH DRUG |
| 11822-3391 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Rite Aid Corporation | OTC MONOGRAPH DRUG |
| 11673-765 | Phenylephrine Hydrochloride 5 mg/15mL; Acetaminophen 325 mg/15mL; Dextromethorphan Hydrobromide 10 mg/15mL Liquid | TARGET CORPORATION | OTC MONOGRAPH DRUG |
| 49483-693 | Phenylephrine Hydrochloride 5 mg/1; Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1 Capsule, Liquid Filled | TIME CAP LABORATORIES, INC. | OTC MONOGRAPH DRUG |
| 41163-998 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | United Natural Foods, Inc. dba UNFI | OTC MONOGRAPH DRUG |
| 0363-0853 | Phenylephrine Hydrochloride 5 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Acetaminophen 325 mg/1 Capsule, Liquid Filled | WALGREENS | OTC MONOGRAPH DRUG |
| 0363-0109 | Acetaminophen 325 mg/1; Guaifenesin 200 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | Walgreens | OTC MONOGRAPH DRUG |
| 67091-394 | Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Phenylephrine Hydrochloride 5 mg/1 Capsule, Liquid Filled | WinCo Foods, LLC | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Daytime Cold and Flu used for?
Uses • temporarily relieves common cold/flu symptoms: • cough due to minor throat and bronchial irritation • sore throat • headache • minor aches and pains • fever
Who makes Daytime Cold and Flu?
Daytime Cold and Flu is listed by 34 labelers in the FDA NDC directory, including Allegiant Health, Amazon.com Services LLC, Best Choice (Valu Merchandisers Company), BETTER LIVING BRANDS, LLC.