Migraine Relief
Acetaminophen, aspirin, caffeine · Tablet · Oral
Active ingredient
Active ingredients (in each geltab) Acetaminophen 250 mg Aspirin 250 mg (NSAID*) Caffeine 65 mg *nonsteroidal anti-inflammatory drug
Purpose
Purposes Pain reliever Pain reliever aid
Uses
Use
• treats migraine
Warnings
Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
• skin reddening
• blisters
• rash If a skin reaction occurs, stop use and seek medical help right away. Allergy alert: Aspirin may cause a severe allergic reaction which may include:
• hives
• facial swelling
• asthma (wheezing)
• shock Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
• more than 2 geltabs in 24 hours, which is the maximum daily amount
• with other drugs containing acetaminophen
• 3 or more alcoholic drinks every day while using this product Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
• are age 60 or older
• have had stomach ulcers or bleeding problems
• take a blood thinning (anticoagulant) or steroid drug
• take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
• have 3 or more alcoholic drinks every day while using this product
• take more or for a longer time than directed Medication overuse headache warning: Headaches may worsen if this product is used for 10 or more days per month. Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause severe nervousness, irritability, sleeplessness, and, occasionally, rapid heart beat. Do not use
• if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer
• with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask a doctor before use if
• you have never had migraines diagnosed by a health professional
• you have a headache that is different from your usual migraines
• you have the worst headache of your life
• you have fever and stiff neck
• you have headaches beginning after or caused by head injury, exertion, coughing or bending
• you experienced your first headache after the age of 50
• you have daily headaches
• you have a migraine so severe as to require bed rest
• you have liver disease
• stomach bleeding warning applies to you
• you have a history of stomach problems, such as heartburn
• you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
• you are taking a diuretic
• you have asthma
• you have problems or serious side effects from taking pain relievers or fever reducers
• you have vomiting with migraine headache Ask a doctor or pharmacist before use if you are
• taking a prescription drug for:
• diabetes
• gout
• arthritis
• under a doctor’s care for any serious condition
• taking any other drug
• taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer Stop use and ask a doctor if
• an allergic reaction occurs. Seek medical help right away.
• you experience any of the following signs of stomach bleeding:
• feel faint
• vomit blood
• have bloody or black stools
• have stomach pain that does not get better
• your migraine is not relieved or worsens after first dose
• new or unexpected symptoms occur
• ringing in the ears or loss of hearing occurs If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Do not use
Do not use
• if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer
• with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
Ask a doctor before use
Ask a doctor before use if
• you have never had migraines diagnosed by a health professional
• you have a headache that is different from your usual migraines
• you have the worst headache of your life
• you have fever and stiff neck
• you have headaches beginning after or caused by head injury, exertion, coughing or bending
• you experienced your first headache after the age of 50
• you have daily headaches
• you have a migraine so severe as to require bed rest
• you have liver disease
• stomach bleeding warning applies to you
• you have a history of stomach problems, such as heartburn
• you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
• you are taking a diuretic
• you have asthma
• you have problems or serious side effects from taking pain relievers or fever reducers
• you have vomiting with migraine headache
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are
• taking a prescription drug for:
• diabetes
• gout
• arthritis
• under a doctor’s care for any serious condition
• taking any other drug
• taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer
Stop use and ask a doctor
Stop use and ask a doctor if
• an allergic reaction occurs. Seek medical help right away.
• you experience any of the following signs of stomach bleeding:
• feel faint
• vomit blood
• have bloody or black stools
• have stomach pain that does not get better
• your migraine is not relieved or worsens after first dose
• new or unexpected symptoms occur
• ringing in the ears or loss of hearing occurs
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
Directions
• do not use more than directed
• adults: take 2 geltabs with a glass of water
• if symptoms persist or worsen, ask your doctor
• do not take more than 2 geltabs in 24 hours, unless directed by a doctor
• under 18 years of age: ask a doctor
Other information
Other information
• store at 20°-25°C (68°-77°F)
• close cap tightly after use
• read all product information before using. Keep this box for important information.
Inactive ingredients
Inactive ingredients black iron oxide, carnauba wax, crospovidone, D&C yellow #10 aluminum lake, FD&C blue #1 aluminum lake, gelatin, glycerin, hypromellose, maltitol solution, medium-chain triglycerides, microcrystalline cellulose, pharmaceutical ink, polyvinyl acetate phthalate, povidone, pregelatinized starch, propylene glycol, stearic acid, titanium dioxide
Questions?
Questions or comments? 1-800-719-9260
Label text from the FDA structured product label by Walgreen Company (revised Aug 24, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Acetaminophen in 12 products
- Aspirin in 12 products
- Caffeine in 12 products
- Ibuprofen in 2 products
- Atropa Belladonna in 1 product
- Bryonia Alba Root in 1 product
- Matricaria Chamomilla Whole in 1 product
- Black Cohosh in 1 product
- Arabica Coffee Bean in 1 product
- Nitroglycerin in 1 product
- Iris Versicolor Root in 1 product
- Sodium Chloride in 1 product
Migraine Relief NDC products (16)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 57344-205 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet | AAA PHARMACEUTICAL, INC. | ANDA |
| 72288-286 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet, Film Coated | Amazon.com Services LLC | ANDA |
| 69452-263 | Ibuprofen 200 mg/1 Capsule, Liquid Filled | Bionpharma Inc. | ANDA |
| 83324-099 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet | CHAIN DRUG MARKETING ASSOCIATION, INC. | ANDA |
| 59779-374 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet, Film Coated | CVS Pharmacy | ANDA |
| 53943-305 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet | DISCOUNT DRUG MART | ANDA |
| 55319-970 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet | Family Dollar (FAMILY WELLNESS) | ANDA |
| 81522-205 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet | FSA STORE INC. | ANDA |
| 72036-305 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet | HARRIS TEETER | ANDA |
| 30142-896 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet, Film Coated | Kroger Company | ANDA |
| 11822-0374 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet, Film Coated | Rite Aid Corporation | ANDA |
| 0363-0374 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet, Film Coated | Walgreen Company | ANDA |
| 0363-1235 | Acetaminophen 250 mg/1; Aspirin 250 mg/1; Caffeine 65 mg/1 Tablet, Film Coated | Walgreen Company | ANDA |
| 0363-0240 | Ibuprofen 200 mg/1 Capsule, Liquid Filled | WALGREENS | ANDA |
| 83004-003 | Turmeric 2 [hp_X]/6g; Curcuma Aromatica Root 4 [hp_X]/6g; Indian Frankincense 4 [hp_X]/6g; Ginger 5 [hp_X]/6g; Feverfew… Powder | Rida LLC | UNAPPROVED DRUG OTHER |
| 43689-0017 | Atropa Belladonna 6 [hp_X]/1; Bryonia Alba Root 6 [hp_X]/1; Matricaria Chamomilla Whole 3 [hp_X]/1; Black Cohosh 6… Tablet | The Magni Company | UNAPPROVED HOMEOPATHIC |
Frequently asked questions
What is Migraine Relief used for?
Use • treats migraine
Who makes Migraine Relief?
Migraine Relief is listed by 15 labelers in the FDA NDC directory, including AAA PHARMACEUTICAL, INC., Amazon.com Services LLC, Bionpharma Inc., CHAIN DRUG MARKETING ASSOCIATION, INC..