Panadol

acetaminophen and diphenhydramine HCl · Tablet, Film Coated · Oral

Over the counter Histamine-1 Receptor Antagonist Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

Active ingredients (in each caplet) Acetaminophen 500 mg Dextromethorphan HBr 15 mg

Purpose

Purposes Pain reliever/Fever reducer Cough suppressant

Uses

Uses Temporarily relieves these symptoms due to a common cold or flu: headache minor aches and pains cough due to minor throat and bronchial irritation minor sore throat pain temporarily reduces fever

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting consult a doctor promptly. Do not use in a child under 12 years of age if you are allergic to acetaminophen with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI)(certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have liver disease cough that occurs with too much phlegm (mucus) cough that lasts or is chronic such as occurs with smoking, asthma or emphysema Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin When using this product do not use more than directed. Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use in a child under 12 years of age if you are allergic to acetaminophen with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI)(certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have liver disease cough that occurs with too much phlegm (mucus) cough that lasts or is chronic such as occurs with smoking, asthma or emphysema

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

When using this product

When using this product do not use more than directed.

Stop use and ask a doctor

Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions do not use more than directed adults and children 12 years of age and over: take 2 caplets every 6 hours, while symptoms persist do not take more than 6 caplets in 24 hours unless directed by a doctor children under 12 years of age: do not use Age Dose adults and children 12 years of age and over 2 caplets every 6 hours children under 12 years of age do not use

Inactive ingredients

Inactive ingredients crospovidone, D&C yellow no. 10 aluminum lake, FD&C red no. 40 aluminum lake, FD&C yellow no. 6 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, silicon dioxide, sodium starch glycolate, stearic acid, talc, titanium dioxide

Questions?

Questions or comments? 1-855-297-3031

Label text from the FDA structured product label by Haleon US Holdings LLC (revised Apr 29, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Panadol NDC products (11)

NDCStrength & formLabelerType
0135-0537Acetaminophen 160 mg/5mL
Suspension
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-0539Acetaminophen 160 mg/5mL
Suspension
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-0607Acetaminophen 325 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-0608Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-0609Acetaminophen 500 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-0620Acetaminophen 500 mg/1; Caffeine 65 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-7011Acetaminophen 500 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-7021Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-7031Acetaminophen 325 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-7033Acetaminophen 500 mg/1; Dextromethorphan Hydrobromide 15 mg/1
Tablet
Haleon US Holdings LLCOTC MONOGRAPH DRUG
0135-7034Acetaminophen 500 mg/1; Chlorpheniramine Maleate 2 mg/1; Dextromethorphan Hydrobromide 15 mg/1
Tablet
Haleon US Holdings LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is Panadol used for?

Uses Temporarily relieves these symptoms due to a common cold or flu: headache minor aches and pains cough due to minor throat and bronchial irritation minor sore throat pain temporarily reduces fever

Who makes Panadol?

Panadol is listed by 1 labeler in the FDA NDC directory, including Haleon US Holdings LLC.