Preparation H Rapid Relief
Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride · Cream · Topical
Active ingredient
Active ingredients Purposes Glycerin 20% Protectant Lidocaine 5% Local anesthetic Phenylephrine HCl 0.25% Vasoconstrictor
Purpose
Active ingredients Purposes Glycerin 20% Protectant Lidocaine 5% Local anesthetic Phenylephrine HCl 0.25% Vasoconstrictor
Uses
Uses for temporary relief of pain, soreness and burning helps relieve the local itching and discomfort associated with hemorrhoids temporarily reduces the swelling associated with irritated hemorrhoidal tissue temporarily provides a coating for relief of anorectal discomforts temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful
Warnings
Warnings For external use only Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression. When using this product wash hands after use. Avoid contact with eyes do not exceed the recommended daily dosage unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days an allergic reaction develops the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Ask a doctor before use
Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression.
When using this product
When using this product wash hands after use. Avoid contact with eyes do not exceed the recommended daily dosage unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator
Stop use and ask a doctor
Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days an allergic reaction develops the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Directions adults: when practical, cleanse the affected area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with a tissue or soft cloth before applying wipe. apply externally to affected area up to 4 times daily. unfold wipe and gently apply to the affected area by patting and then discard. children under 12 years of age: ask a doctor
Other information
Other information store at 20-25°C (68-77°F) for best results, flush only one at a time
Inactive ingredients
Inactive ingredients aloe barbadensis leaf juice, anhydrous citric acid, benzyl alcohol, edetate disodium, propylene glycol, purified water, sodium benzoate
Questions?
Questions or comments? Call weekdays 9 AM to 5 PM EST at 1-800-99PrepH or 1-800-997-7374
Label text from the FDA structured product label by Haleon US Holdings LLC (revised Jan 8, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Lidocaine in 3 products
- Phenylephrine Hydrochloride in 3 products
- Glycerin in 2 products
- Petrolatum in 1 product
Preparation H Rapid Relief NDC products (3)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 0573-0554 | Lidocaine 50 mg/1; Phenylephrine Hydrochloride 2.5 mg/1; Glycerin 200 mg/1 Cloth | Haleon US Holdings LLC | OTC MONOGRAPH DRUG |
| 0573-2843 | Petrolatum 150 mg/g; Phenylephrine Hydrochloride 2.5 mg/g; Glycerin 144 mg/g; Lidocaine 50 mg/g Cream | Haleon US Holdings LLC | OTC MONOGRAPH DRUG |
| 0573-2890 | Lidocaine 50 mg/g; Phenylephrine Hydrochloride 2.5 mg/g Spray | Haleon US Holdings LLC | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Preparation H Rapid Relief used for?
Uses for temporary relief of pain, soreness and burning helps relieve the local itching and discomfort associated with hemorrhoids temporarily reduces the swelling associated with irritated hemorrhoidal tissue temporarily provides a coating for relief of anorectal discomforts temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful
Who makes Preparation H Rapid Relief?
Preparation H Rapid Relief is listed by 1 labeler in the FDA NDC directory, including Haleon US Holdings LLC.